Yunus E. Demiray
Dr. Yunus Emre Demiray
Department of Genetics & Molecular Neurobiology
I am a postdoctoral researcher since August-2021 in our group. My research deals with signalling cascades that are important during neuronal development. I use molecular and pharmacological tools on primary neuronal cultures to analyse morphology and protein biochemistry. In my current project, I study how integrin receptors and its downstream cytoskeleton elements interact and control dendritic growth. Furthermore, by combining viral interventions with behavioral characterization, I will focus on how such structural changes on dendrites can translate to physiological and behavioural modulations in vivo.
Education
B.Sc. in Molecular Biology and Genetics, Bilkent University, Ankara, Turkey 2012
M.Sc. in Integrative Neuroscience, Otto-von-Guericke University, Magdeburg, Germany 2015
Dr. rer. nat. in Neurobiology, Otto-von-Guericke-University, Magdeburg, Germany 2021
2025
Peer-reviewed journal article
The serine/threonine kinase NDR2 regulates integrin signaling, synapse formation, and synaptic plasticity in the hippocampus
Ángel, del Miguel; Tsutiya, Atsuhiro; Hayani, Hussam; Madencioglu, Deniz; Kul, Emre Ufuk; Çalişkan, Gürsel; Demiray, Yunus Emre; Dityatev, Alexander; Stork, Oliver
In: Journal of neurochemistry - Oxford : Wiley-Blackwell, Bd. 169 (2025), Heft 6, Artikel e70094, insges. 15 S.
2024
Peer-reviewed journal article
The NDR family of kinases - essential regulators of ageing
Del Angel, Miguel; Jonischkies, Kevin; Demiray, Yunus E.; Loaiza Zambrano, Allison Gabriela; Stork, Oliver
In: Frontiers in molecular neuroscience - Lausanne : Frontiers Research Foundation, Bd. 17 (2024), insges. 20 S.
2023
Peer-reviewed journal article
Comparison of three common inbred mouse strains reveals substantial differences in hippocampal GABAergic interneuron populations and in vitro network oscillations
Çalışkan, Gürsel; Demiray, Yunus E.; Stork, Oliver
In: European journal of neuroscience - Oxford [u.a.] : Wiley, Bd. 58 (2023), Heft 6, S. 3383-3401
2022
Peer-reviewed journal article
Fear engrams and NPYergic circuit in the dorsal dentate gyrus determine remote fear memory generalization
Raza, Syed Ahsan; Klinger, Katharina; Ángel, Miguel; Demiray, Yunus Emre; Caliskan, Gürsel; Kreutz, Michael R.; Stork, Oliver
In: bioRxiv beta - Cold Spring Harbor : Cold Spring Harbor Laboratory, NY . - 2022, insges. 28 S.
2021
Peer-reviewed journal article
Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function
Madencioglu, Deniz A.; Çalişkan, Gürsel; Yuanxiang, Pingan; Rehberg, Kati; Demiray, Yunus E.; Kul, Emre Ufuk; Engler, Alexander; Hayani, Hussam; Bergado Acosta, Jorge R.; Kummer, Anne; Müller, Iris; Song, Inseon; Dityatev, Alexander; Kähne, Thilo; Kreutz, Michael R.; Stork, Oliver
In: iScience - Amsterdam : Elsevier, Bd. 24 (2021), Heft 8, Artikel 102868, insges. 23 S.
Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits
Tripathi, Kuldeep; Demiray, Yunus Emre; Kliche, Stefanie; Jing, Liang; Hazra, Somoday; Hazra, Joyeeta Dutta; Richter-Levin, Gal; Stork, Oliver
In: Neurobiology of Stress - Amsterdam [u.a.] : Elsevier, Bd. 15 (2021), Artikel 100350, insges. 12 S.
2020
Peer-reviewed journal article
Region-specific involvement of interneuron subpopulations in trauma-related pathology and resilience
Regev-Tsur, Stav; Demiray, Yunus Emre; Tripathi, Kuldeep; Stork, Oliver; Richter-Levin, Gal; Albrecht, Anne
In: Neurobiology of disease - Orlando, Fla. : Academic Press - Bd. 143.2020, Art.-Nr. 104974, insgesamt 11 Seiten
Dietary phytoestrogens modulate aggression and activity in social behavior circuits of male mice
Sandhu, Kiran Veer; Demiray, Yunus Emre; Yanagawa, Yuchio; Stork, Oliver
In: Hormones and behavior - Orlando, Fla. : Acad. Press - Volume 119 (2019), Artikel 104637
2019
Abstract
Role of Ndr2 kinase in substrate-specific neurite growth and spine development
Demiray, Yunus Emre; Tsutiya, Atsuhiro; Madencioglu Kul, Deniz Ashan; Lee, Dain; Stork, Oliver
In: 37th Göttingen Neurobiology Conference - Neurowissenschaftliche Gesellschaft - 2019, Artikel T2-1B - (Neuroforum, Band 25, Suppl. 1) [Konferenz: 13th Meeting of the German Neuroscience Society, Göttingen, March 20-23, 2019]
Peer-reviewed journal article
Depletion of dietary phytoestrogens reduces hippocampal plasticity and contextual fear memory stability in adult male mouse
Çalışkan, Gürsel; Raza, Syed Ahsan; Demiray, Yunus E.; Kul, Emre; Sandhu, Kiran V.; Stork, Oliver
In: Nutritional neuroscience - Abingdon, Oxon : Routledge, Taylor and Francis Group . - 2019 [Online first]
2018
Peer-reviewed journal article
Ndr2 kinase controls neurite outgrowth and dendritic branching through [alpha]1 integrin expression
Demiray, Yunus E.; Rehberg, Kati; Kliche, Stefanie; Stork, Oliver
In: Frontiers in molecular neuroscience - Lausanne : Frontiers Research Foundation - Bd. 11.2018, Art.-Nr. 66, insges. 11 S.
Filamin A phosphorylation at serine 2152 by the serine/threonine kinase Ndr2 controls TCR-induced LFA-1 activation in T cells
Waldt, Natalie; Seifert, Anke; Demiray, Yunus Emre; Devroe, Eric; Turk, Benjamin E.; Reichardt, Peter; Mix, Charlie; Reinhold, Annegret; Freund, Christian; Müller, Andreas Johann; Schraven, Burkhart; Stork, Oliver; Kliche, Stefanie
In: Frontiers in immunology - Lausanne : Frontiers Media - Bd. 9.2018, Art.-Nr. 2852, insges. 16 S.
2017
Peer-reviewed journal article
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience
Raza, Ahsan Syed; Albrecht, Anne; Çalişkan, Gürsel; Müller, Bettina; Demiray, Yunus Emre; Ludewig, Susann; Meis, Susanne; Faber, Nicolai; Hartig, Roland; Schraven, Burkhart; Leßmann, Volkmar; Schwegler, Herbert; Stork, Oliver
In: Nature Communications - [London] : Nature Publishing Group UK - Vol. 8.2017, Art. 189, insgesamt 15 S.